Impact of SARS-2 in areas where SARS-1 was prevalent in 2002-04?

In summary, it is believed that SARS-CoV-2 has had a less significant impact on areas where SARS-CoV-1 had previously raged. It is also believed that there is cross immunity between the two viruses.
  • #1
mktsgm
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TL;DR Summary
How the SARS-CoV-2 has affected the area where the SARS-CoV-1 had affected in 2002-04? Was it more severe or less severe?
We know that SARS-CoV-1 affected the world in 2002-04. Many countries including China were affected then.

I want to know, how the SARS-CoV-2 is faring now, in the areas which had already been affected by SARS-CoV-1 earlier. Dr. Beda M Stadler the former director of the Institute for Immunology at the University of Bern, has recently mentioned as
"It also became known that Sars-CoV-2 had a less significant impact in areas in China where Sars-1 had previously raged"
in a recent article in the Swiss magazine Weltwoche (World Week) on June 10th.

Do we have more data on these lines? Was there any study to prove this hypothesis?

Similarly do we have any study on the impact of SARS-CoV-2 in the areas where MERS (2012-13) was more prevalent?

Thanks.
 
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Likes atyy and Andrew Mason
Biology news on Phys.org
  • #2
First of all SARS-1 did not affect very many people even in the "hotspots". The outbreak in Toronto was one of the largest outside of China and it had about 400 cases. There were a total of about 8000 cases worldwide. So I don't think it is possible to make any obvious conclusions.

Furthermore, Toronto had a high infection rate of COVID-19 (15000 cases).

Since China's population is around 1.4 billion it would not be possible to conclude anything without looking at infection rates among SARS-1 survivors.

There were even fewer MERS cases (about 2500) and proportionately fewer survivors with a death toll of around 900.

AM
 
  • #3
Point taken. Thanks
 
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Likes atyy
  • #4
Actually this has become an interesting subject area, some very recent work not only suggests significant cross immunity with SARS but immunity in populations exposed to neither of these viruses. They ruled out the other coronaviruses that infect humans as the reason for this but identified a Coronavirus that infects animals as a possible cause. If this is confirmed it has huge implications for future vaccine work.
https://www.nature.com/articles/s41586-020-2550-z
 
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Likes atyy, jim mcnamara and BillTre

Related to Impact of SARS-2 in areas where SARS-1 was prevalent in 2002-04?

1. What is the difference between SARS-1 and SARS-2?

SARS-1 and SARS-2 are both caused by coronaviruses, but they are different strains. SARS-1 was first identified in 2002 and caused a global outbreak in 2002-2004, while SARS-2, also known as COVID-19, was first identified in 2019 and has caused a global pandemic. SARS-2 is more easily transmissible and has a higher mortality rate compared to SARS-1.

2. How does the prevalence of SARS-1 in 2002-2004 affect the impact of SARS-2 in the same areas?

Areas that experienced a high prevalence of SARS-1 in 2002-2004 may have some level of immunity against SARS-2 due to cross-reactivity of antibodies. However, the immunity may not be strong enough to prevent infection or severe illness from SARS-2.

3. What are the potential factors that contribute to the impact of SARS-2 in areas where SARS-1 was prevalent in 2002-2004?

Some potential factors that may contribute to the impact of SARS-2 in areas where SARS-1 was prevalent in 2002-2004 include population density, healthcare infrastructure, and public health measures in place. These factors can affect the spread and severity of the virus in a community.

4. Is there a higher risk of reinfection with SARS-2 in areas where SARS-1 was prevalent in 2002-2004?

There is currently no evidence to suggest that individuals who were previously infected with SARS-1 are at a higher risk of reinfection with SARS-2. However, it is still important for individuals to follow recommended precautions to prevent infection and protect their health.

5. How can we use the lessons learned from SARS-1 to mitigate the impact of SARS-2 in areas where it was prevalent in 2002-2004?

Lessons learned from the SARS-1 outbreak, such as the importance of early detection, contact tracing, and quarantine measures, can be applied to mitigate the impact of SARS-2 in areas where it was prevalent in 2002-2004. Additionally, ongoing research and development of vaccines and treatments can also help to reduce the impact of SARS-2 in these areas.

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