Are There Any New Classes of Antibiotics for Treating Antibiotic Resistance?

[rockind78]

I am being asked to discuss antibiotic resistance for a take-home exam and I was wondering if I am missing any classes of antibiotics. This is what I have:

*Sulfonamides
*Quinolones
*Penicillins
*Cephalosporins
*Tetracyclines
*Aminoglycosides
*Macrolides
*Chloramphenicol

*The book I am referencing is now going on five years old, so I wanted to know if anything signifigant has popped up. Any thoughts? thanks!

 

[Monique]

erythromycins (which target the ribosome, like tetracyclins and aminoglycosides)

lincosamindes, clindamycin and lincomycin against anaerobic pathogens

fluroquinolones (related to the older quinolones) are synthetic antibiotics

macrolydes have a macrocyclic lactone chemical structure, antibiotics belonging to this group are erythromycin and clarithyromycin.

Just look up those names I just gave, since I am not entirely sure if they are classes or actual antibiotics.

 

[iansmith]

myxopyronin - DNA-dependent polymerase
CBR703 (This one is fairly new) - inhibits RNA polymerase http://www.sciencedaily.com/releases/2003/10/031024064511.htm

In your list you have mention antibiotics that are not class. For example, Penicilin and Cephalosporins are a beta-lactam but both can are sometimes referred to as different classes.

This is a table showing some older antibiotics with their class and the year of discovery
http://www.asmusa.org/memonly/asmnews/may99/table1.htm

Here a list
http://www.chemicalland21.com/arokorhi/info/ANTIBIOTICS.htm

 

[agnostictheist]

Carbapenems

again ather kind of beta-lactam

you better of classing them has eg: beta-lactams (which is there mode of action -- the polygylcan wall..and X-bridge) and then provide examples:

eg:

BETA-LACTAMS:

Clavams - and good example is clavulanic acid, which is used in a mixture, in order to combat anti-biotic resistance, say for example against a Zn protase? (think its protase), mechinsm.

Pencillians eg penams

Carbapenems - meropenem

Monobactams,
and
Oxacephems: which are bascily Oxgyen analogues to Cephems (which are cephalosporins)

 

[rockind78]

Thank you everyone for your responses. They are VERY helpful!.
I think my professor is going to end up with more info than he wants because of the way he phrased the question, but he usually enjoys reading up on stuff he is not familiar with.

 

[kopilka]

Look here - http://antibioticsfor.com/antibiotic-classes.phtml" .
Good luck in your studies!

 

[Ryan_m_b]

Look here - http://antibioticsfor.com/antibiotic-classes.phtml" .
Good luck in your studies!

Welcome to PF Kopilka and well done! I think you've broken the record for http://en.wikipedia.org/wiki/Bump_(Internet)#Necrobumps". As you can see from the date above people's names this thread has not been active for 8 years, the person's studies were completed long ago!

 

[kopilka]

Useful information is needed and after 8 years of ago)))

 

[nucleargirl]

wow, people here really know stuff! impressive.

 

[nucleargirl]

like can you think of anywhere else where you'd ask a random question like that and actually get answers?! from people who seem to know what they're talking about?!