- #106
pinball1970
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Hope you well soonkyphysics said:Got my new updated COVID booster yesterday.
Feel horrrrrible today! Like a truck ran over me and I have zero energy left to even move. Gosh - this fatigue is major (even beyond or equal to my worst days with diabetic fatigue). Massive headache, chills, and tiredness.
Literally could not concentrate on any work and called it a day. It'd take me extended time to even do basic arithmetic today. . . . .let's see how long this lasts.
Good luck to all getting their boosters!
Thanks!pinball1970 said:Hope you well soon
kyphysics said:Thanks!
Saw this today and thought others might like:
Wait, so we no longer track COVID cases, yet we know cases and hospitalizations are up? Am I misunderstanding?Laroxe said:Well it's clear that Covid 19 isn't over, and it might be with us for some time, but the reports of side effects to the new vaccine are a bit worrying. It is starting to look as if the regulators are using different standards in regulating this vaccine, and this seems to be reflected in the different recommendations seen in different countries. Considering the evidence that the monovalent vaccine does result in much higher antibody levels towards the current variants, this does, at least suggest, a higher risk of immunogenic adverse effects. I wonder if the shorter evaluation period, with fewer subjects, would have picked this up.
There is currently an increase in cases and hospitalisations, which interestingly doesn't appear linked to the newer variants. The increase is nothing like the numbers seen in last summer's surge, and might simply reflect the increasing travel seen in the summer months. Having said that the fact that case numbers are no longer monitored, we have no clear idea of numbers in the community.
https://www.medscape.com/s/viewarticle/it-may-be-time-pay-attention-covid-again-2023a1000ipk
IIRC, the stated rational was (paraphrased)kyphysics said:is there a reason they don't do bivalent anymore.
Mine is booked for 25th October so I'll see if different from last year which was bivalent. (UK)kyphysics said:Wait, so we no longer track COVID cases, yet we know cases and hospitalizations are up? Am I misunderstanding?
I know my local hospital no longer posts daily case counts. They stopped in early 2023, IIRC.
As for the latest boosters (I got Moderna's Spikevax), is there a reason they don't do bivalent anymore. My last booster before Spikevax was a Pfizer bivalent one. Is there anything wrong with a bivalent booster? I tried searching, but don't see anything. Searches just say bivalent boosters should not be used anymore.
Getting to endemic status as per Influenza A with seasons and annual jabs for vulnerable groups for A and covid is where we are. I will take that.Tom.G said:IIRC, the stated rational was (paraphrased)
'Almost everyone has already been either vaccinated or has already caught the Covid version that the old vaccines cover. The hospitals are no longer overloaded so there is no longer an emergency.'
My first impression was, Perhaps hard-nosed, but eminently practical!
(Do you take a Cold Medicine when you don't have a Cold or the sniffles?)
Cheers,
Tom
It was decided virtually everywhere that the sort of population level surveillance that used to happen no longer serves a purpose. There are still some types of surveillance used, the testing of waste water for Covid RNA and other virus particles seems to be used in some places. This can, it seems, give a reasonable indicator of the rate of infection in the population. Hospitalisations and deaths are always recorded, so changes in them continue to be monitored.kyphysics said:Wait, so we no longer track COVID cases, yet we know cases and hospitalizations are up? Am I misunderstanding?
I know my local hospital no longer posts daily case counts. They stopped in early 2023, IIRC.
As for the latest boosters (I got Moderna's Spikevax), is there a reason they don't do bivalent anymore. My last booster before Spikevax was a Pfizer bivalent one. Is there anything wrong with a bivalent booster? I tried searching, but don't see anything. Searches just say bivalent boosters should not be used anymore.
Sending over this COVID resource in case it's helpful in your research or daily work: Expontum (https://www.expontum.com/) - Helps students and researchers quickly find knowledge gaps and identify what research projects have been completed before. https://www.expontum.com/knowledgegaps.php?subj=COVID-19Tom.G said:Popular article referring to the BA.2 variant:Popular article: (many words, little data)
https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html
Preprint article referring to the BA.2 variant:Preprint article: (At 52 pages, too many words!)
https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf
[edited 1hr. after posting: Added preprint Abstract]
Cheers,
Tom
I just got my updated COVID booster a couple hours. Hope it doesn't make me feel horrible tomorrow.kyphysics said:Got my new updated COVID booster yesterday.
Feel horrrrrible today! Like a truck ran over me and I have zero energy left to even move. Gosh - this fatigue is major (even beyond or equal to my worst days with diabetic fatigue). Massive headache, chills, and tiredness.
Literally could not concentrate on any work and called it a day. It'd take me extended time to even do basic arithmetic today. . . . .let's see how long this lasts.
Good luck to all getting their boosters!
This is the conclusion of a team of researchers from University of Toronto, who conducted studies on mice into the role of the protein in cases of COVID-19.
They report that men only have one copy of the ACE2 gene - meaning that, when infected, too much of the protein is occupied by the virus and its protective role is compromised.
While the study has only been conducted in mice, it is likely the same mechanism is contributing to sex-based differences in Covid outcomes in humans as well.
Furthermore, the team proposes that synthetic ACE2 proteins might be given to people as protection in high Covid-risk situations, and as a therapy in hospitals.
Just a bit of a sore triceps. Took a couple of Ibuprofen and all is okay.dlgoff said:Hope it doesn't make me feel horrible tomorrow.
Fixed that for you.dlgoff said:Just a bit of a soretricepsdeltoid muscle.
Thank you sir.berkeman said:Fixed that for you.
Just got my triple. No soreness.dlgoff said:Just a bit of a sore triceps. Took a couple of Ibuprofen and all is okay.
I lifted weights - before and after. I can feel some irritation on my left side, but nothing on my right.berkeman said:I shot hoops after getting my flu vax yesterday in my left deltoid to try to help loosen it up, and it seems to have helped. Only a tiny soreness today. The bigger question is which deltoid should I get the COV booster in tomorrow... I think I'll go for the left one again and go shoot more hoops after...
So, how's the arm?berkeman said:I think I'll go for the left one again ...
It's okay. Deltoid muscle soreness from the 2nd shot was more than the flu vax a couple days ago, so I took a couple IB this morning and still shot hoops this afternoon. So far no side effects from the latest COV booster.dlgoff said:So, how's the arm?
Off-topic: Are you any good at hoops? My favorite sport (to watch and play)!berkeman said:still shot hoops this afternoon. So far no side effects from the latest COV booster.
Since it's OT, I'll respond via PM.kyphysics said:Off-topic: Are you any good at hoops? My favorite sport (to watch and play)!
Yeah, this latest booster a couple days ago was no problem at all. A bit of a sore deltoid (more than from the flu shot a couple days earlier -- weird), but no side effects at all. I've held off my usual high-intensity MTB rides the last couple of days to be cautious, but tomorrow I hit the single track!kyphysics said:Anecdotally, the people I know getting Moderna's vax and boosters have had less symptoms/side-effects.
Was that your first vax for Covid? The booters now are single-dose.dlgoff said:My deltoid muscle is still sore from the Moderna Spikevax I had on October 3rd. Don't know if I going to get the second dose.
My COVD-19 Vaccination Record Card says "Reminder! Return for a second dose!"berkeman said:Was that your first vax for Covid? The booters now are single-dose.
Only if this was your first Covid vax ever...dlgoff said:My COVD-19 Vaccination Record Card says "Reminder! Return for a second dose!"