- #1
Lotic7
- 12
- 0
I had this synthesis question on my last midterm and got it wrong. I was wondering if someone here could point me in the right direction. It is a thiophene synthesis that starts off with a 1,4 diketone, but instead of P2S5 or Lawesson's reagent, H2S and HCl are used. I tried to hydrate one of the carbonyls and have H2S do a back side attack. This was marked wrong and I only got 1 mark out of 12 for this wonderful synthesis. What is the proper way to do this synthesis. How efficient is this synthesis when hydrogen sulphide and hydrochloric acid are used instead of P2S5.
Thanks for the assistance
Thanks for the assistance