T2 in Nuclear Magnetic Resonance & MRI

In summary, T2 is the spin-spin relaxation time in MRI and NMR. It measures the dephasing of spins due to their interaction with surrounding spins, and is affected by the inhomogeneity of the local spin field. T2 is one of two relevant times in this process, the other being T1 (spin-lattice relaxation time). T1 and T2 measure different dynamics and both contribute to the overall understanding of the material's behavior in an external magnetic field. While T2 is specific to MRI and NMR, T1 and T2 are both important in understanding the behavior of nuclear spins in general.
  • #1
riezer
58
0
I want to understand MRI and what exactly is T2. I have read the November issue of Sci-am and I'm still confused what exactly is T2 as it has different descriptions. The article "The Incredible Shrinking Scanner" by Bernhard Blumich:


"The system can also monitor the precessing spins as they fall randomly out of sync (T2 graph)"

"The synchronous precession of magnetic spins induces an oscillating voltages in the coil that decays with a characteristic T2 time constant for each spin type as the spins fall out of synchrony."

Can you give in your own worlds what you think is T2 for MRI in particular and NMR in general?

Also I guess in MRI, they only deal with Hydrogen atoms in water while NMR handle the rest of the elements beside Hydrogen?

What are the best references or web sites about MRI out there (I have read the wiki but it is not so good).

Thank you.
 
Physics news on Phys.org
  • #2
T2 is known as the spin-spin relaxation time.

When the material in question is put in an external magnetic field, the nuclear spins will be aligned parallel, or antiparallel to this field. How, if you apply an RF field 90 degrees to this direction, you will cause the spins to change, causing the net bulk magnetization to flip 90 degrees. After this short pulse, the material will try to get back to its original configuration (it is still in this static, external field).

There are two characteristic times that are relevant here, T1 (spin-lattice relaxation time), and T2 (spin-spin relaxation time). The name itself tells you the relevant dynamics involved in these times. These all measures the time it takes for the system to go back to where it was, but each one measure different dynamics. T2 measure the "dephasing" of the spins due to the surrounding spins. Right after the 90 degree pulse, the spins are aligned in the plane perpendicular to the z-direction, i.e. the direction of the static external field. Once the 90-degree pulse is over, the spin component in this plane will start to dephase and will go back to being random so that the net spin this this plane is zero (all the spin components in the z-direction will go back to being parallel or antiparallel to the external field). The dephasing rate depends on the inhomogeneity of the local spin field. So it is the interaction strength of the each spin with other spins around it that will determine how fast it will dephase. So that's why it is called the spin-spin relaxation time. It gives a measure of the spin inhomogeneity within the sample.

Zz.
 

Related to T2 in Nuclear Magnetic Resonance & MRI

1. What is T2 in Nuclear Magnetic Resonance & MRI?

T2, also known as transverse relaxation time, is a measure of how quickly the excited nuclear spins in a sample lose their energy and return to their equilibrium state. It is an important parameter in Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) as it can provide information about the molecular environment and tissue properties.

2. How is T2 measured in NMR & MRI?

In NMR, T2 is measured by applying a pulse of radiofrequency energy to the sample and then measuring the decay of the resulting signal. In MRI, T2 is indirectly measured by using specialized sequences that manipulate the magnetic field gradients to produce different contrast between tissues, which is then translated into T2 values.

3. What affects T2 values in NMR & MRI?

T2 values can be affected by a variety of factors, including the molecular structure and composition of the sample, interactions with neighboring molecules, and magnetic field inhomogeneities. In MRI, T2 values can also be influenced by the imaging parameters, such as echo time and sequence type.

4. How is T2 used in NMR & MRI applications?

T2 values are used in a variety of NMR and MRI applications, such as identifying different types of molecules in a sample, characterizing tissue properties, and detecting abnormalities in tissues. In MRI, T2-weighted images can provide information about water content, inflammation, and pathology.

5. What are the limitations of using T2 in NMR & MRI?

While T2 is a useful parameter in NMR and MRI, it has some limitations. The accuracy of T2 measurements can be affected by artifacts and noise, making it challenging to interpret in some cases. Additionally, T2 is only one piece of the puzzle and needs to be combined with other parameters to fully understand the sample or tissue being studied.

Similar threads

Replies
4
Views
1K
  • Atomic and Condensed Matter
Replies
5
Views
2K
  • Classical Physics
Replies
24
Views
3K
  • Electromagnetism
Replies
4
Views
1K
Replies
14
Views
2K
  • Quantum Physics
Replies
1
Views
977
  • Atomic and Condensed Matter
Replies
4
Views
4K
Replies
4
Views
2K
  • Atomic and Condensed Matter
Replies
6
Views
4K
Replies
2
Views
1K
Back
Top