Questions on synthesizing Fluorine 18

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In summary: Fluorine 18 in PET scans and creating a neutron source with Americium 241. He is wondering if there are alternative ways to produce Fluorine 18, such as through neutron bombardment, and if it is possible to create a simple Deuteron emitter. However, due to the unstable nature of Fluorine 18 and Deuteron, it is unlikely that they can be produced through these methods. The best way to produce Fluorine 18 is through a cyclotron, and a source of energetic deuterons can be created by ionizing deuterium gas within a particle accelerator.
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Strat-O
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I have a couple questions but first some background:

Fluorine 18 is used in PET scans as a beta+ emitter. Generally it is created with an 11-18 MeV cyclotron by bombarding Oxygen 18 with protons. I read a paper that said there was an alternative way to produce F 18 by the NEON-20(DEUTERON, ALPHA)FLUORINE-18 reaction that only requires about 1-3 MeV. My question is, are there other ways that any of you know of to transmute a relatively stable isotope into F 18 by, say neutron bombardment?

Another question:
If you wrap Americium 241 with Beryllium foil you create a neutron source that gives off about 5 MeV neutrons. What's neat about that is it's all passive--nothing to plug in, it just works. Is there a way that you can create a Deuteron emitter that works just as simply?

Thanks!

Marlin
 
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  • #2
Natural, stable F is 19F. 18F has one less neutron for that number of protons, which is why it decays by positron emission. Because it's on the neutron-poor side of the line of optimal stability, you really can't produce it by irradiating a target material with neutrons.

A deuteron is quite an unstable nucleus - it has relatively low binding energy per nucleon, which is why it likes to react with other light nuclei in reactions such as D-D and D-T fusion, for example.

Because it's relatively weakly bound, it's very unlikely to be found as the product of a nuclear reaction, analogous to the 9Be(alpha, n)12C reaction that goes on inside an alpha-Be neutron source.

To make a source of energetic deuterons, you ionise deuterium gas within the ion source of a particle accelerator such as a cyclotron, just as you would with unenriched hydrogen if you were using a proton beam.
 
  • #3
Thank you Minerva. Looks like good info.

Marlin
 

Related to Questions on synthesizing Fluorine 18

1. What is Fluorine 18 and why is it important?

Fluorine 18 is a radioactive isotope of the element fluorine. It is important because it is commonly used in positron emission tomography (PET) imaging, a medical imaging technique that allows for the detection of diseases and abnormalities in the body.

2. How is Fluorine 18 synthesized?

Fluorine 18 is synthesized through a nuclear reaction called proton bombardment. A proton beam is directed at a target material, typically oxygen-18, which produces Fluorine 18 as a byproduct.

3. What are the potential uses of synthesized Fluorine 18?

Synthesized Fluorine 18 is mainly used in PET imaging for medical purposes, but it also has potential applications in biomedical research, drug development, and environmental studies.

4. What are the benefits and risks of using Fluorine 18 in medical imaging?

The benefits of using Fluorine 18 in medical imaging include its short half-life, which allows for quick decay and reduces the amount of radiation exposure to patients. However, there are potential risks associated with radiation exposure, so proper safety measures must be taken when handling Fluorine 18.

5. How is the purity and quality of synthesized Fluorine 18 ensured?

The purity and quality of synthesized Fluorine 18 is ensured through rigorous testing and quality control measures. This includes analyzing the radioactivity levels, chemical composition, and potential contaminants in the final product before it is used in any applications.

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