Ochem, name R or S for this? Why?

  • Thread starter Lo.Lee.Ta.
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Therefore, it is R.In summary, the 2nd chiral carbon of the cephalexin molecule is R because it is bonded to an S and an N, which have a greater atomic weight than O. The Carbon bonded to the S and N is second priority, making the overall molecule R.
  • #1
Lo.Lee.Ta.
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Why is the 2nd chiral carbon of cephalexin molecule R? I thought the N has first priority, then the Carbon with the double bond to the O would be second (b/c has no H), and the Carbon bonded to the S would be third priority b/c it has a hydrogen, and of course, H is fourth... But then it would be S if that was the case... Why is it R?
 
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  • #2
Never mind. Well, not that anyone was going to answer anyway.

But the chiral carbon in question is bonded to an S and an N. S and N have a greater atomic weight than O. So the H doesn't matter.

The Carbon bonded to the S and N is second priority.
 

Related to Ochem, name R or S for this? Why?

1. What is Ochem?

Ochem, short for "Organic Chemistry", is a branch of chemistry that deals with the study of carbon-containing compounds and their properties, structures, reactions, and synthesis.

2. What does R or S mean in Ochem?

R and S are the two possible configurations for chiral molecules in Ochem. R stands for rectus (meaning "right" in Latin) and S stands for sinister (meaning "left" in Latin).

3. How do you determine if a molecule is R or S in Ochem?

The R or S designation is determined by the Cahn-Ingold-Prelog (CIP) rules, which assign priorities to the substituents attached to a chiral carbon based on the atomic number of the atoms directly attached to the carbon. The molecule is then viewed so that the lowest priority substituent is pointing away from the observer, and the remaining three substituents are arranged in order of decreasing priority. If the order is clockwise, the molecule is designated as R. If the order is counterclockwise, the molecule is designated as S.

4. Why is it important to know if a molecule is R or S in Ochem?

The R or S designation is crucial in Ochem as it determines the stereoisomeric relationship between two molecules. This information is important in predicting and understanding the properties and reactions of the molecule, as well as in drug development and synthesis.

5. Can a molecule be both R and S in Ochem?

No, a molecule can only have one R or S designation. This is because the CIP rules prioritize the substituents attached to a chiral carbon, resulting in a unique arrangement of the substituents. However, a molecule may have multiple chiral centers, each with its own R or S designation.

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