Nucleoli and Nucleus: The Relationship and Role in the Nuclear Matrix

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In summary, the nucleolus is believed to physically separate itself from the nucleoplasm through a process called phase separation, similar to how oil droplets can separate from water. This is a current and rapidly developing area of research, with recent studies showing promising results. For more information, a recent review on the topic can be found at the link provided.
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If nucleoli does not have a clear membrane,wouldn't it get mixed up with substances in the nuclear matrix present in the nucleus ?
 
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The nucleolus is though to separate itself from the rest of the nucleoplasm via physical mechanisms resembling phase separation (like how oil droplets can separate from water). This is a very active area of research with many new results in the past couple of years. Here's a recent review on the topic: http://www.sciencedirect.com/science/article/pii/S0955067415000435
 
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Ygggdrasil said:
phase separation (like how oil droplets can separate from water).
That's the perfect answer.Thank you :smile:
 

Related to Nucleoli and Nucleus: The Relationship and Role in the Nuclear Matrix

1. What is the function of the nucleolus in the nucleus?

The nucleolus is responsible for the production and assembly of ribosomes, which are essential for protein synthesis in the cell. It also plays a role in regulating cell growth and division.

2. How does the nucleolus interact with the nucleus?

The nucleolus is located within the nucleus and is connected to the rest of the nucleus through a network of proteins and fibers known as the nuclear matrix. This allows for communication and coordination between the nucleolus and other nuclear components.

3. What is the relationship between the nucleolus and the nuclear matrix?

The nucleolus is a specialized structure within the nuclear matrix, which is the framework that supports and organizes the contents of the nucleus. The nucleolus plays an important role in maintaining the integrity and function of the nuclear matrix.

4. How does the nucleolus contribute to overall cell function?

The nucleolus is involved in the production of ribosomes, which are essential for protein synthesis in the cell. It also plays a role in the regulation of cell growth and division, as well as in responding to cellular stress and damage.

5. What happens to the nucleolus during cell division?

During cell division, the nucleolus breaks down and reassembles in order to produce new ribosomes for the daughter cells. This ensures that each new cell has the necessary components for protein synthesis and cellular function.

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