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I have been studying about the physiology of hunger. I have studied about the hormones that are involved in the process of hunger, like ghrelin, leptin, pancreatic polypeptide, cholecystokinin, cholecystokinin (CCK) and the neurons like AgRP, POMC and neuropeptide Y (NPY) etc.
I understand that ghrelin urges us to eat. Leptin gives us satiation.
But I am confused as to how hunger is triggered at first instance.
Can anyone throw some light on simple terms on the connection among the energy level, ATP, hunger hormones and hunger neurons so that I get clarity on complete physiology on hunger?
I understand that ghrelin urges us to eat. Leptin gives us satiation.
But I am confused as to how hunger is triggered at first instance.
- What senses what, to trigger hunger?
- Is it ghrelin that initiates the whole process? Is energy level determines hunger/
- If so how ghrelin (or whatever initiates it) senses the energy need?
- Is energy need is synonymous (only) to the ATP level?
- How and at which state the hypothalamus (AgRP, POMC & NPY) is involved?
- What is the role of stomach, pancreas & intestines?
- How to distinguish hunger, appetite and satiety?
Can anyone throw some light on simple terms on the connection among the energy level, ATP, hunger hormones and hunger neurons so that I get clarity on complete physiology on hunger?
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