Biochem Help: Cell Cycle Protein Synthesis Q&A

In summary, the question asked about which protein is predominantly synthesized during the S phase of the cell cycle. After discussing and eliminating some choices, it was determined that histones play a critical role in DNA stability and are therefore the answer to the question. The answer was confirmed by a paper linked by Ian.
  • #1
Roxanita
2
0
Biochem help :(??

Hi :smile:
I have seen great people on this forum, can anybody please help me with this question?

Q- The majority of cellular proteins and RNA are synthesized throughout the cell cycle and are only interrupted briefly during M phase. Synthesis of which of the following proteins occurs predominantly in S phase of the cell cycle?

A) Cyclins

B) DNases

C) Histones

D) RNA polymerases

E) snRNPs (small nuclear ribonucleoproteins)

F) Tubulins

thanks in advance :shy:
 
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  • #2
Do you know what is the major evenet during the S-phase? This should eliminated four of the choice that do not have any related role with to this event. One choice has a direct role in contolling the S-phase events whereas the last remaining protein is an absolute require for DNA stability.

this paper gives the answer
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=325892
 
  • #3
Thanks Ian

I read about it. Histones is the answer. Sorry I am studying Biochemistry at med school, but was trying to solve questions before doing a good review. Sorry.
Thanks again.
 

1. What is the cell cycle and why is it important?

The cell cycle is the process by which a cell grows, replicates its DNA, and divides into two daughter cells. This cycle is important for the growth and development of an organism, as well as for the maintenance and repair of tissues.

2. What are the stages of the cell cycle?

The cell cycle is divided into two main stages: interphase and mitosis. Interphase is further divided into three phases: G1 (growth), S (DNA synthesis), and G2 (growth and preparation for division). Mitosis is divided into four phases: prophase, metaphase, anaphase, and telophase.

3. What is protein synthesis and how is it related to the cell cycle?

Protein synthesis is the process by which cells make proteins. It is an essential part of the cell cycle, as proteins are necessary for cell growth, division, and function. During the S phase of interphase, DNA is replicated in preparation for cell division. This DNA contains the instructions for making proteins, which are then synthesized during the G2 phase before cell division occurs.

4. What role do cell cycle proteins play in regulating the cell cycle?

Cell cycle proteins are responsible for controlling the progression of the cell cycle. They act as checkpoints, ensuring that the cell is ready to move on to the next phase and preventing any errors or abnormalities. If these proteins are not functioning properly, it can lead to uncontrolled cell growth and potentially cancer.

5. How does the cell cycle differ in cancer cells?

In cancer cells, the cell cycle is disrupted and uncontrolled. Mutations in cell cycle proteins can cause these cells to divide and grow at a faster rate than normal cells. Additionally, cancer cells may also bypass or ignore checkpoints, allowing them to continue dividing and forming tumors.

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